A post-GWAS Method for Highly Informative Associations in Complex Diseases by Allen Roses, M.D.,Barbaresco Pharmaceuticals, Inc. from pioglitazone Watch Video
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Description: Speaker: Allen D. Roses, M.D., CEO, Barbaresco Pharmaceuticals, Inc.nnA highly polymorphic polyT marker at a single locus [rs10524523] in intron 6 of TOMM40 was found to extend the association of APOE4 to include APOE3 and APOE2. The TOMM40 data are informative for prediction of age of onset of Mild Cognitive Impairment due to Alzheimer’s Disease over the next five years for 97% of Caucasians, based on age and genotype between 65-83 years old. Phylogenetic mapping has facilitated the enrichmen
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